Principal Biologist
About the role
About Proxima
Proxima is a frontier AI and data generation company discovering the next generation of proximity therapeutics by making protein interactions programmable. The platform combines foundation-model machine learning, a scalable data generation engine, and partnerships exceeding $5B in collaborations across leading biopharma and tech organizations.
Neo-1 Foundation Model
Neo-1 is an all-atom foundation model that combines state-of-the-art structure prediction and molecular generation in a single system. It enables rapid exploration of chemical and structural space for high value targets and unlocks small molecule proximity therapeutics like molecular glues with AI.
Structural Interactomics Platform
An advanced platform built on proprietary XLMS technology equipped with next-generation mass spectrometry instrumentation. This platform produces proteome-scale maps of protein interactions and identifies small molecules that modulate proximity.
Role Impact
Together with Neo-1, the integrated system is capable of co-folding protein complexes while generating candidate small molecules to influence those interactions. Proximity-based therapeutics represent one of the most promising frontiers in modern drug discovery.